A brand new mind imaging examine has concluded that autism probably is not attributable to defective connections to the amygdala.
A prevailing speculation of autism spectrum dysfunction has held that folks with the situation have poorer neural connections in sure mind areas, together with the amygdala.
Nevertheless, researchers discovered no proof that folks with autism had amygdala connections that differed considerably to these present in individuals with out autism.
The amygdala is a small, almond-shaped construction within the mind that performs a key function in processing feelings and social cues, researchers defined.
For the examine, researchers analyzed high-quality MRI mind scans from 488 individuals, together with 212 with autism.
The staff targeted on the neural connections emanating from the amygdala when the individuals weren’t actively engaged in any duties.
Common variation in connectivity to the amygdala was related in individuals with and with out autism, outcomes confirmed.
The outcomes had been the identical when researchers checked out particular subregions of the amygdala, researchers added.
The brand new examine was printed within the American Journal of Psychiatry.
“You will need to be aware that we don’t conclude that amygdala [connectivity] is usually typical in autism. As an alternative, we conclude that the proof for atypical [connectivity] of the amygdala in autism is weak at greatest, and unreliable,” concluded the researchers led by Dorit Kliemann, an assistant professor of psychological and mind sciences with the College of Iowa.
The researchers stated in a information launch from the American Psychiatric Affiliation that extra mind scan analysis ought to be executed to additional perceive the variations in individuals with and with out autism, calling it “an funding value prioritizing if we’re to higher perceive and delineate the neurobiological substrates of autism.”
Extra data:
The College of California-Davis has extra on the amygdala and autism.
Dorit Kliemann et al, Resting-State Practical Connectivity of the Amygdala in Autism: A Preregistered Massive-Scale Examine, American Journal of Psychiatry (2024). DOI: 10.1176/appi.ajp.20230249
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